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The Substance

Have you ever dreamt of a better version of yourself?

★ 7.1/10from 6,422 votes2024 · 2h 21m · Horror, Science Fiction
HorrorScience Fiction

A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.

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Top cast

Demi Moore
Demi MooreElisabeth
Margaret Qualley
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Dennis Quaid
Dennis QuaidHarvey
Edward Hamilton-Clark
Edward Hamilton-ClarkFred
Gore Abrams
Gore AbramsOliver
Oscar Lesage
Oscar LesageTroy
Christian Erickson
Christian EricksonMan at Diner
Robin Greer
Robin GreerMale Nurse
Tom Morton
Tom MortonDoctor
Hugo Diego Garcia
Hugo Diego GarciaDiego - Boyfriend

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